ProSAS Web Application
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Require structure annotation: Sequence identity (%): Coverage (%):

Short tutorial:

  • Please make sure the JavaScript is activated and that Java is required. For details on how to get Java and how to activate JavaScript follow this link
  • Example Queries are ENSG (all human genes), ENSMUSG (all mouse genes), ENSRNOG (all rat genes) and ENSPTRG (all chimp genes) for the Ensembl Gene ID or e.g. ENST (all human transcripts) for Transcript searches.
    To restrict a query to entries with modelled protein structures please select the Require structure annotation checkbox and set the sequence identity and coverage parameters accordingly. We suggest to use a minimal sequence identity of at least 30%. Queries are matched onto identifiers if they are a substring of the corresponding identifier
  • Results are opened in a new tab of the application. Click on a result row to view the details of e.g. a gene entry
  • Transcripts: to view details for a specific transcript e.g. open a exon view in the gene details window and follow a transcript link
  • Structures: to explore a structure, click the show structure information button in the transcript details view. You may select different templates by clicking on the red bars below the exons. Please note: Most structure annotations represent predictions and some must be handled with care!
If you need more help or want to learn more about the features of the ProSAS database or want to download data please follow this link to the ProSAS tutorial

Help

If you have any comments or suggestions please write an email to fabian.birzele@bio.ifi.lmu.de



Publications

If you find ProSAS helpful for your own research please cite: Fabian Birzele, Robert Kueffner, Franziska Meier, Florian Oefinger, Christian Potthast and Ralf Zimmer, ProSAS: A database for analyzing alternative splicing in the context of protein structure, Nucleic Acids Research, 2008, Vol. 36, Database issue D63-D68 (Article)

You may also be interested in: Fabian Birzele, Gergely Csaba and Ralf Zimmer, Alternative Splicing and Protein Structure Evolution Nucleic Acids Reasearch, 2008, Vol. 36:2, 550-558, 2008 (Article)

The ProSAS database is developed by: Fabian Birzele, Eva Hoffmann, Robert Kueffner, Franziska Meier, Florian Oefinger, Christian Potthast, Yanxiang Zhou and Ralf Zimmer